[Creative Biolabs 공식대리점 관련 업무대행/수입] APP Gene-Engineered Cell Model Products

어스바이오는 Creative Biolabs 공식대리점 관련 업무대행/수입 전문 취급점으로서 모든 제품을 전문적으로 취급 및 공급하고 있습니다.
Creative Biolabs의 Gene Products을 소개드립니다.
 

The Amyloid Precursor Protein (APP) functions as a vital component in Alzheimer's disease development. Precisely developed cell models provide crucial instruments for research on APP function and the effects of gene mutations related to diseases.
 

Featured APP Gene-Engineered Cell Model Categories

• AD Mutation Models: Examine the specific impacts of variants such as APP Swedish (KM670/671NL), APP London (V717I), APP Indiana (V717F), and the APP N-terminal Val225Ala (V225A) mutation, which is associated with progressive dementia and influences tau protein interaction. Investigate how these mutations affect amyloid processing, tau pathology, and general cellular function.
• APP Overexpression Models: Study the consequences of increased APP levels on cellular pathways relevant to AD, such as amyloid-beta production and synaptic dysfunction. Ideal for understanding dosage effects and downstream signaling.
• APP Knock-Out Models: Elucidate the fundamental role of APP by examining cellular phenotypes in the absence of functional APP protein. Essential for understanding baseline functions and the impact of APP loss.
• APP Knock-In Models: Investigate the subtle effects of specific APP variants or domains by precisely inserting them into the endogenous APP locus. Offers a more physiologically relevant context for studying specific alterations.
• APP Tagged Cell Lines: Facilitate protein localization, interaction studies, and purification with our range of APP cell lines expressing tagged proteins (e.g., GFP, FLAG). Ideal for biochemical and cell biology assays.